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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC5L
All Species:
19.39
Human Site:
S654
Identified Species:
35.56
UniProt:
Q99459
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99459
NP_001244.1
802
92251
S654
M
S
H
G
E
L
S
S
E
A
Y
N
Q
V
W
Chimpanzee
Pan troglodytes
XP_518512
698
80173
T564
S
G
N
K
K
G
K
T
V
G
F
G
T
N
N
Rhesus Macaque
Macaca mulatta
XP_001100220
802
92232
S654
M
S
H
G
E
L
S
S
E
A
Y
N
Q
V
W
Dog
Lupus familis
XP_532156
908
104015
S760
M
S
H
G
E
L
S
S
E
A
Y
N
Q
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6A068
802
92171
S654
M
S
H
G
E
L
S
S
E
A
Y
N
Q
V
W
Rat
Rattus norvegicus
O08837
802
92199
S654
M
S
H
G
E
L
S
S
E
A
Y
N
Q
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511089
803
92142
N655
M
S
H
G
E
L
S
N
E
A
Y
N
Q
V
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957378
800
91707
M652
M
G
H
G
D
L
S
M
E
A
Y
N
Q
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624906
781
89377
L637
M
A
H
G
E
L
S
L
D
S
Y
T
T
V
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178584
701
79489
L571
L
E
T
P
M
T
E
L
Q
K
A
E
E
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92948
844
95748
L655
M
G
H
E
N
K
T
L
D
D
F
V
E
A
H
Baker's Yeast
Sacchar. cerevisiae
Q03654
590
67712
M469
A
I
N
K
E
P
H
M
V
P
E
D
T
V
D
Red Bread Mold
Neurospora crassa
Q7SAF6
779
87489
D624
Q
V
L
M
E
I
K
D
K
P
K
P
E
E
V
Conservation
Percent
Protein Identity:
100
86.4
99.7
87.4
N.A.
98
97.8
N.A.
93.9
N.A.
N.A.
84
N.A.
N.A.
63.9
N.A.
58.2
Protein Similarity:
100
86.6
100
88.2
N.A.
99.1
99.2
N.A.
97.6
N.A.
N.A.
92.3
N.A.
N.A.
77
N.A.
70.2
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
80
N.A.
N.A.
60
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
N.A.
80
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.6
31.4
44.3
Protein Similarity:
N.A.
N.A.
N.A.
63
46.6
60.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
54
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
16
8
0
8
0
0
8
% D
% Glu:
0
8
0
8
70
0
8
0
54
0
8
8
24
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% F
% Gly:
0
24
0
62
0
8
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
70
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
16
8
8
16
0
8
8
8
0
0
0
0
% K
% Leu:
8
0
8
0
0
62
0
24
0
0
0
0
0
0
0
% L
% Met:
70
0
0
8
8
0
0
16
0
0
0
0
0
8
0
% M
% Asn:
0
0
16
0
8
0
0
8
0
0
0
54
0
8
8
% N
% Pro:
0
0
0
8
0
8
0
0
0
16
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
0
0
54
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
47
0
0
0
0
62
39
0
8
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
8
8
0
0
0
8
24
0
0
% T
% Val:
0
8
0
0
0
0
0
0
16
0
0
8
0
70
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _